Peripheral Arterial Disease

Peripheral Arterial Disease – Symptoms, Diagnosis, Treatment, and Prevention

Symptoms, Diagnosis, Treatment, and Prevention are all important aspects to consider when dealing with Peripheral Arterial Disease. Learn about each of these areas to help you make the best treatment decisions for your individual situation.


Symptoms of peripheral arterial disease are caused by atherosclerosis, a buildup of plaques on the walls of the arteries. These fatty deposits reduce the flow of blood. They can also block the arteries, making it difficult for blood to flow to your heart and brain. This can lead to a heart attack or stroke. The disease can also cause death.

Symptoms of peripheral arterial disease include leg pain, cramping, and leg pain while walking. These symptoms are usually relieved when you rest. If you experience pain during rest, it is important to seek treatment. You may need to take a blood pressure test or an ultrasound of the legs. The doctor will also evaluate your family history.

Symptoms of peripheral arterial disease can occur when there is a blockage in the arteries in your legs. In severe cases, the affected limb may have to be amputated. Some symptoms of the peripheral arterial disease can be reversed, and medications can be used to reduce pain and increase blood flow.

Some of the signs and symptoms of peripheral arterial disease include pain or cramping when walking, leg heaviness, and fatigue during exercise. Some people experience pain in the calf muscles, buttocks, or thighs. The pain may also be worse when you elevate your leg. If you have symptoms of peripheral arterial disease, seek treatment immediately.

A doctor will diagnose peripheral arterial disease by using a physical exam, symptoms, and risk factors. He will also evaluate your family history of cardiovascular disease. The doctor may order an angiogram to view spot blockages. A Doppler ultrasonography can also be performed to determine blood flow.

A doctor can also diagnose peripheral arterial disease by using an ankle-brachial pressure index, which is a test to determine whether the blood flow to the foot is normal. This index is performed after a treadmill exercise. The doctor will compare the pressure in your leg to the pressure in your arm. If the pressure in your arm is higher than the pressure in your leg, you may have peripheral artery disease.

Symptoms of peripheral arterial disease may include reduced blood flow, and cramping in the calf, buttocks, or thighs. These symptoms can be painful and uncomfortable. Medications are used to reduce pain, increase blood flow, and reduce the risk of a heart attack or stroke.


Identifying and treating peripheral arterial disease is a valuable means of improving a patient’s functional status. However, diagnosing and treating the disease is not always straightforward. Even in the medical community, there is a lack of understanding about the disease. In general practice, diagnosis is based on a detailed history and physical examination.

In order to diagnose the disease, the most accurate method is to take an ankle-brachial index (ABI). This index is the difference between blood pressure in the ankle and upper arm. A normal range is between 0.9 and 1.4. This measurement can be performed non-invasively. However, this index is not very reliable when the vascular stiffness is high. If the ABI is lower than a normal value, a diagnosis of peripheral arterial disease may be made.

Another test to diagnose the disease is to calculate the toe-brachial index. This index is calculated from a segmental blood pressure measurement. This index is calculated after a patient has been at rest for 10 minutes.

If the ABI is lower than the normal value, a diagnosis of peripheral arterial and stenosis is made. In addition, the peripheral arterial disease is a risk factor for atherothrombotic events in other vascular beds. This risk factor is particularly common in people with diabetes. If the ABI is lower than 0.4, it is important to consider antiplatelet medication. Antiplatelet drugs are used to prevent acute coronary syndromes and prevent transient ischemic attacks. Antiplatelet medication may also help to relieve the symptoms of peripheral arterial disease.

In addition to the ankle-brachial index, a physical examination can be used to diagnose peripheral arterial disease. This examination can include pulse abnormalities and gait alterations. Often, peripheral arterial disease is asymptomatic. However, it is important to remember that asymptomatic patients have a higher risk of functional decline and cardiovascular morbidity.

The diagnosis of peripheral arterial disease should be a holistic evaluation. This means examining the whole vascular system and considering whether there are other causes for the patient’s symptoms. It is important to make preventive lifestyle changes as well. It is also important to identify and treat a peripheral arterial disease early to prevent the development of critical ischemia.


Approximately 12 percent of the population suffers from peripheral arterial disease (PAD), which is a condition where arteries to the lower limbs become narrowed or clogged. It is the most common cause of peripheral vascular disease. It is often accompanied by atherosclerosis, which is a buildup of fatty plaque in the arteries. This can lead to blockage of the arteries and ischemia.

Treatment of PAD involves risk modification, exercise, and medications. Aggressive risk modification includes smoking cessation, control of hypertension, diabetes, and dyslipidemia, and the use of ACE inhibitors or statins. It also includes structured exercise therapy.

In addition, a non-invasive vascular examination laboratory can be used to determine the location of occlusive lesions. These tests include angiography and magnetic resonance angiography. If an occlusion is suspected, a percutaneous transluminal angioplasty is the treatment of choice. However, these procedures are not a substitute for a comprehensive non-invasive vascular examination.

Angiogenesis, also known as capillary growth, is a process that occurs when the endothelial cells of an ischemic tissue become active. This process is induced by hypoxia and the release of cytokines. It is important to note that angiogenesis is dependent upon non-tissue resident cells. It is therefore not a substitute for a large occluded transport artery.

A non-invasive test that can help in the diagnosis of peripheral artery disease is the ankle-brachial index (ABI). An index higher than 50 is an indication of critical ischemia, which could result in limb amputation. An index lower than 40 indicates that the patient is not at risk for developing an ischemic attack.

In severe cases of PAD, a revascularization is a treatment option. For patients with extensive disease, conventional surgery is usually the best option. Antithrombotic agents may be used to prevent thrombosis after peripheral bypass surgery. However, these drugs have not been shown to improve the outcome of the procedure.

Peripheral artery disease is a common condition, but it is underdiagnosed. The early detection of PAD can reduce the risk of secondary vascular events, such as stroke and ischemic ulcers.

In addition, peripheral artery disease is associated with a high mortality rate. This is partly due to the comorbidity of peripheral artery disease with other cardiovascular diseases. Hence, it is important to identify these conditions early in order to maximize the patient quality of life.

Preventing complications

Keeping complications of peripheral arterial disease at bay is important. This condition is a slow and progressive circulatory disorder that affects the brain, heart, and lower limbs. This disease is caused by plaque build-up on the walls of the arteries. The plaque restricts blood flow and allows only a small amount of oxygen to reach the limbs and organs. The condition can be treated with medication and lifestyle modifications.

The best way to prevent complications of peripheral arterial disease is to know your risk factors. These risk factors include smoking, hypertension, and diabetes. You should also get screened for chronic kidney disease, and be aware of any signs or symptoms of heart disease or stroke. If you have any of these conditions, be sure to seek medical attention right away.

If you suspect you have peripheral arterial disease, ask your doctor to perform an ultrasound. This imaging test gives an anatomic view of your arteries and reports on the flow of blood through them. The images can help your doctor determine if you need surgical intervention. The test can also identify areas of arterial blockage. If you have PVD, you should also be screened for coronary artery disease and ulcers in the legs.

Treatment for PVD can include medical management, exercise therapy, and lifestyle modifications. You may also need to take peripheral vasodilators or change your diet. Medications and lifestyle changes can help you control your blood pressure, cholesterol, and blood sugar levels, which can decrease the risk of heart disease and stroke. You may also need to have surgery to remove the affected limb.

Peripheral arterial disease can be a life-threatening condition, so it’s important to get it diagnosed right away. The condition can lead to complications such as heart attack, stroke, and amputation of your legs. Fortunately, there are many ways to prevent complications of peripheral arterial disease, and many people do not have any symptoms. A screening test such as the ankle-brachial index is also available. You may also be able to prevent complications of peripheral arterial disease by exercising regularly, not smoking, and eating a healthy diet.

Health Sources:

Health A to Z. (n.d.).

U.S. National Library of Medicine. (n.d.).

Directory Health Topics. (n.d.).

Health A-Z. (2022, April 26). Verywell Health.

Harvard Health. (2015, November 17). Health A to Z.

Health Conditions A-Z Sitemap. (n.d.).

Susan Silverman

Susan Silverman

Susan Silverman is a Healthy Home Remedies Writer for Home Remedy Lifestyle! With over 10 years of experience, I've helped countless people find natural solutions to their health problems. At Home Remedy Lifestyle, we believe that knowledge is power. I am dedicated to providing our readers with trustworthy, evidence-based information about home remedies and natural medical treatments. I love finding creative ways to live a healthy and holistic lifestyle on a budget! It is my hope to empower our readers to take control of their health!

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