Intracranial Aneurysms and Flow Diversion Stents
Flow diversion stents are devices that have been developed for the treatment of aneurysms. This type of therapy is designed to reconstruct aneurysms by modifying the flow pattern in the parent artery. The goal of the procedure is to eliminate residual flows into the aneurysm, thereby preventing rupture and a fatal outcome. Although these devices are effective in remodeling the parent artery lumen, they do not eliminate the risk of ischemic complications. Therefore, it is important to study the long-term effects of these devices.
The goal of this study is to evaluate the safety of flow diversion technology for the treatment of wide-necked aneurysms, especially those located in perforating arteries. The authors performed a prospective, multicenter study on patients treated with flow diverters for intracranial aneurysms at bifurcation sites. The patients were treated with a stent alone, with coils, or with a combination of both techniques. They were evaluated by angiography and Flat Detector CT Angiography (FDCAT) to determine whether the flow diverter had any effect on the occlusion status of the aneurysm. These devices have been shown to be able to successfully treat complex aneurysms in perforating arteries. However, they are still not understood thoroughly. Flow diverter embolization is effective in remodeling the parent artery lumen, thereby reducing the risk of ischemic complications. However, there are some risks related to stents, such as device deformity and device kinking. The authors evaluated these risks by performing follow-up angiography at 5-13 months, depending on the clinical status of the patient.
The results of this study indicate that stent-assisted coil embolization is a safe procedure. However, it may not result in recanalization of the aneurysm as quickly as stents alone. In addition, stent-assisted coiling may result in a higher rate of complications. This could have an impact on the clinical outcome of the procedure. The authors recommend performing a larger series of patients to determine the effectiveness of flow diversion stents.
Twenty-two patients were treated for acutely ruptured complex aneurysms. The average size of the aneurysm was 16.7 mm. In addition, the majority of aneurysms were saccular in shape, with a mean diameter of 5.3 mm. The locations of the aneurysms were in the basilar artery, the posterior cerebral artery, and the Pcom. In addition, one patient suffered a remote parenchymal hematoma. A single stent was deployed from the basilar artery to the right posterior cerebral artery.
In the study, 68 patients had wide neck aneurysms that were unfavorable in shape or location. These patients had an average wall pressure of 4.19 mmHg. Flow diversion therapy was effective in lowering the wall pressure and achieving complete occlusion in 21 of the aneurysms. In the remaining nine aneurysms, a partial occlusion was observed. The remaining six aneurysms showed no change in flow. In two aneurysms, a remote parenchymal hematoma was observed, although this was not a major complication. Flow diversion therapy has been used successfully to treat aneurysms in the perforating arteries, and the authors recommend that this technology be used for the treatment of wide-neck aneurysms.
Among all the different types of aneurysms in the brain, saccular aneurysms are the most common. A saccular aneurysm is a bulge on the wall of a blood vessel. It occurs at a branch point where the flow divides. These aneurysms are considered degenerative because of the degenerative changes that occur within the blood vessel wall. They can occur in any part of the brain, though they tend to occur in the anterior circulation. This is because the blood circulates to the brain through two paired arteries. This arrangement creates greater pressure at certain locations of the aneurysm, which causes the aneurysm to grow.
Cerebral saccular aneurysms are thought to be associated with hemodynamically-induced degenerative vascular changes in the brain. The inner muscular layer of the blood vessel wall becomes weakened, which causes the aneurysm. This may be due to congenital weakness or ongoing degenerative processes. Other causes include trauma, renal disease, and chronic inflammatory conditions. The majority of saccular aneurysms are benign. However, they may rupture, leading to subarachnoid hemorrhage, a serious emergency that can result in coma or death.
In the USA, approximately 10-12 million people are diagnosed with aneurysms in their brains. The most common type of aneurysm is a saccular aneurysm, though fusiform aneurysms are also common. These aneurysms are thought to occur due to a genetic predisposition. They tend to be spherical in shape with a neck at the base. Saccular aneurysms tend to point in the direction of the blood flow, while fusiform aneurysms have a flat surface. Saccular aneurysms are also thought to occur at the branchings of the Circle of Willis.
The incidence of saccular aneurysms is thought to be around 2% of the general population. Most aneurysms occur in the anterior circulation, though they can also occur in the posterior circulation. In the USA, there are about 27,000 new aneurysms diagnosed each year. Symptoms of a saccular aneurysm include pain, bleeding, or a mass effect. These symptoms may occur in a similar way to other medical conditions, making it hard to know if a saccular aneurysm is a culprit. If you are concerned about a saccular aneurysm in your brain, you should consult a neurosurgeon. Your physician will ask you about any medications you are taking and will perform a CT scan to determine if you have a saccular aneurysm. A CT scan is a computerized imaging technique that uses X-rays and computer technology to produce detailed images of any part of the body. It is the most accurate and definitive tool for diagnosing and treating cerebral aneurysms.
Saccular aneurysms are often caused by atherosclerotic disease, although they may also occur in autoimmune disorders such as Takayasu arteritis. The risk of aneurysm growth increases with hypertension, diabetes, and smoking. Other less common causes include trauma, aortic infections, and chronic inflammatory conditions. Some saccular aneurysms may also be caused by a tear in the inner layer of the blood vessel wall. The inner muscular layer is thought to rupture without warning, leading to an aneurysm.
Health A to Z. (n.d.). HSE.ie. https://www2.hse.ie/az/
U.S. National Library of Medicine. (n.d.). https://www.ncbi.nlm.nih.gov/
Directory Health Topics. (n.d.). https://www.healthline.com/directory/topics
Health A-Z. (2022, April 26). Verywell Health. https://www.verywellhealth.com/health-a-z-4014770
Harvard Health. (2015, November 17). Health A to Z. https://www.health.harvard.edu/health-a-to-z
Health Conditions A-Z Sitemap. (n.d.). EverydayHealth.com. https://www.everydayhealth.com/conditions/